2010 PIAA District IV Football Playoff Brackets
Class A
- Southern Columbia (1)68
- @ Southern Columbia
November 12 - 7:00 pm - Canton (4)52
- Line Mountain (2)57
- @ Line Mountain
November 12 - 7:00 pm - Muncy (3)20
- Southern Columbia (1)48
- @ Southern Columbia
November 19 - 7:00 pm - Line Mountain (2)13
- Southern Columbia (1)
- Champion
Class AA
- Danville (1)62
- @ Danville
November 12 - 7:00 pm - Wyalusing (8)20
- North Penn (4)14
- @ North Penn
November 12 - 7:00 pm - Mount Carmel (5)45
- Lewisburg (2)21
- @ Bucknell University
November 12 - 5:00 pm - Bloomsburg (7)20
- Towanda (3)56
- @ Towanda
November 12 - 7:00 pm - Hughesville (6)21
- Danville (1)38
- @ Danville
November 19 - 7:00 pm - Mount Carmel (5)28
- Lewisburg (2)39
- @ Bucknell University
November 20 - 4:00 pm - Towanda (3)14
- Danville (1)13
- @ Danville
November 26 - 7:00 pm - Lewisburg (2)18
- Lewisburg (2)
- Champion
Class AAA
- Selinsgrove (1)35
- @ Selinsgrove
November 12 - 7:00 pm - Columbia Montour Vo-Tech (4)7
- Shikellamy (2)23
- @ Shikellamy
November 12 - 7:00 pm - Shamokin (3)17
- Selinsgrove (1)27
- @ Selinsgrove
November 19 - 7:00 pm - Shikellamy (2)35
- Shikellamy (2)
- Champion
Class AAAA
- Easton (1)39
- @ Easton
November 12 - TBA - Del Val (8)7
- Pleasant Valley (4)21
- @ Pleasant Valley
November 12 - 7:00 pm - East Stroud South (5)35
- Whitehall (2)41
- @ Whitehall
November 12 - TBA - Wyoming Valley West (7)27
- Nazareth (3)63
- @ Nazareth
November 12 - TBA - Williamsport (6)24
- Easton (1)68
- @ Easton
November 19 - 7:00 pm - East Stroud South (5)20
- Whitehall (2)21
- @ Whitehall
November 19 - 7:00 pm - Nazareth (3)6
- Easton (1)13
- @ Easton
November 27 - 7:00 pm - Whitehall (2)10
- Champion